Changes between Version 3 and Version 4 of SOPs/AlphaFold
- Timestamp:
- 04/22/24 22:03:28 (10 months ago)
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SOPs/AlphaFold
v3 v4 2 2 3 3 === Background === 4 The success of DeepMind's AlphaFold protein folding algorithmin the CASP14 structural prediction assessment has been widely celebrated and has profoundly invigorated the structural biology community. Today, if you have a protein sequence for which you'd like to learn a high quality predicted structure, an excellent place to start is the [https://alphafold.ebi.ac.uk/ AlphaFold Protein Structure Database]. An alternative database to search is the [https://esmatlas.com/resources?action=fold ESM Metagenomic Atlas], where you may find predicted structures for orphan proteins with few sequence homologs.4 The success of [https://www.nature.com/articles/s41586-021-03819-2 DeepMind's AlphaFold protein folding algorithm] in the CASP14 structural prediction assessment has been widely celebrated and has profoundly invigorated the structural biology community. Today, if you have a protein sequence for which you'd like to learn a high quality predicted structure, an excellent place to start is the [https://alphafold.ebi.ac.uk/ AlphaFold Protein Structure Database]. An alternative database to search is the [https://esmatlas.com/resources?action=fold ESM Metagenomic Atlas], where you may find predicted structures for orphan proteins with few sequence homologs.