Changes between Version 7 and Version 8 of SOPs/AlphaFold


Ignore:
Timestamp:
04/23/24 06:30:53 (9 months ago)
Author:
twhitfie
Comment:

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  • SOPs/AlphaFold

    v7 v8  
    22
    33=== Background ===
    4 The success of [https://www.nature.com/articles/s41586-021-03819-2 DeepMind's AlphaFold protein folding algorithm] in the CASP14 structural prediction assessment has been widely celebrated and has profoundly invigorated the structural biology community. Today, if you have a protein sequence for which you'd like to learn a high quality predicted structure, an excellent place to start is the [https://alphafold.ebi.ac.uk/ AlphaFold Protein Structure Database]. An alternative database to search is the [https://esmatlas.com/resources?action=fold ESM Metagenomic Atlas], where you may find predicted structures for orphan proteins with few sequence homologs.
     4The success of [https://www.nature.com/articles/s41586-021-03819-2 DeepMind's AlphaFold protein folding algorithm] in the [https://onlinelibrary.wiley.com/toc/10970134/2021/89/12 CASP14 structural prediction assessment] has been widely [https://www.nature.com/articles/d41586-020-03348-4 celebrated] and has profoundly invigorated the structural biology community. Today, if you have a protein sequence for which you'd like to learn a high quality predicted structure, an excellent place to start is the [https://alphafold.ebi.ac.uk/ AlphaFold Protein Structure Database]. An alternative database to search is the [https://esmatlas.com/resources?action=fold ESM Metagenomic Atlas], where you may find predicted structures for orphan proteins with few sequence homologs.
    55
    66=== Running AlphaFold using ChimeraX ===