| 19 | | * Assigning weights: There is no standard way to assign weights, however, it should reflect some logical order. GSEA uses the correlation (between expression and phenotype) to assign weights, if the list is not pre-ordered or ranked. A similar scheme can be used to rank the genes, other options includes using the t-score, or a scoring scheme that takes into account both log ratio and p-value. |
| | 19 | * Assigning weights: There is no standard way to assign weights, however, it should reflect some logical order. GSEA uses the correlation between expression and phenotype to assign weights, if the list is not pre-ordered or ranked. A similar scheme can be used to rank genes by log2 ratio, t-statistic, or a scoring scheme that takes into account both log ratio and p-value. |
