Changes between Version 55 and Version 56 of SOPs/rna-seq-diff-expressions


Ignore:
Timestamp:
12/18/17 09:44:38 (7 years ago)
Author:
thiruvil
Comment:

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  • SOPs/rna-seq-diff-expressions

    v55 v56  
    164164       * [http://www.bioconductor.org/packages/release/bioc/html/NOISeq.html NOISeq] ([wiki:SOPs/rna-seq-diff-expressions/NOISeq more detail])
    165165      * In our hands, all of these methods appear to work fine.  Note, however, that the scale of the p-values from baySeq are much different from those of DESeq and edgeR.  For example, a gene may have a baySeq p-value of 1e-15 but a DESeq p-value of 1e-300.
     166      * Technical replicates can be collapsed (eg. summed or use  collapseReplicates()in DESeq2)
     167
    166168    * Scripts with sample code are in the BaRC code repository at \\wi-files1\BaRC_Public\BaRC_code\R (and see the vignettes in the R packages linked above).
     169   
    167170
    168171  * **Identifying differentially expressed genes**