Changes between Version 19 and Version 20 of SOPs/vcf
- Timestamp:
- 07/27/16 11:46:34 (9 years ago)
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SOPs/vcf
v19 v20 90 90 91 91 * Assess Hardy-Weinberg Equilibrium (HWE) using an exact test, deviation from HWE may indicate selection, population mixing or non-random mating, see [[http://www.ncbi.nlm.nih.gov/pubmed/7498780 | PMID 7498780 ]] for more details. 92 * Use [[https://vcftools.github.io/index.html | vcftools]] option "--hardy" to report a p-value for each site to assess deviation from HWE. VCF file must have genotypes of individuals explicitly reported.92 * Use [[https://vcftools.github.io/index.html | vcftools]] option "--hardy" to report a p-value for each site to assess deviation from HWE. 93 93 {{{ 94 #VCF file must have genotypes of individuals explicitly reported 94 95 vcftools --vcf myVariants.vcf --hardy --out myVariantsHWE 95 96 }}}